Research Groups

RESEARCH UNIT: Molecular Nanoscience and Organic Materials (NANOMOL)

Centre of Nanotechnology and Molecular Materials (NANOMOL)

NANOMOL contributions have been focused to provide new molecule-based multifunctional advanced materials to be used in tissue engineering, in drug delivery and for the fabrication of electronic devices.

The Centre of Nanotechnology and Molecular Materials (Nanomol) is a research group with wide expertise in the synthesis, processing and study of molecular and polymeric materials, mainly for electronic and biomedical applications, with tailored chemical, electrical, magnetic and biological properties. We continuously generate new knowledge in our basic and applied research projects regarding the micro and nano structuring of  funcional molecular materials. 


  • Prof. Jaume Veciana - Research Professor 
  • Prof. Concepció Rovira - Research Professor 
  • Dr. Nora Ventosa - Research Scientist 
  • Dr. Marta Mas-Torrent - Research Scientist 
  • Dr. José Vidal - Tenured Scientist 
  • Dr. Imma Ratera - Tenured Scientist 
  • Dr. Núria Crivillers - Tenured Scientist 
  • Dr. Elena Laukhina - CIBER Researcher 
  • Dr. Elisabet González - CIBER- Postdoctoral Researcher 
  • Dr. Judith Guasch - Ramon y Cajal Researcher 
  • Dr. Mariana Köber - Postdoctoral Researcher 
  • Dr. Raphael Pfattner - Postdoctoral Researcher 
  • Dr. Tommaso Salzillo - Postdoctoral Researcher 
  • Dr. Nathaly Segovia - Postdoctoral Researcher 
  • Dr. Judit Morlà - Postdoctoral Researcher 
  • Eduardo Pérez - Postdoctoral Researcher 
  • Guillem Vargas - Postdoctoral Researcher 
  • Dolores Bueno - PhD Researcher 
  • Aída Carreño - PhD Researcher 
  • Nerea González - PhD Researcher 
  • Jinghai Li - PhD Researcher 
  • Marc Martínez - PhD Researcher 
  • Jesus Alejandro de Sousa Rodriguez - PhD Researcher 
  • Adrián Tamayo - PhD Researcher 
  • Judit Tomsen - PhD Researcher 
  • Songbai Zhang - PhD Researcher 
  • Lidia Ballell - PhD Researcher 
  • Roberto Fabião Santos Abreu - PhD Researcher 
  • José Ignacio Catalan  - PhD Researcher 
  • Sara Ruiz Molina – PhD Researcher 
  • Ángel Campos - PhD Researcher 
  • Simona Ricci- PhD Reseracher 
  • Lamiaa Fijahi- PhD Researcher 
  • Miquel Castellote – PhD Researcher 
  • Amable Bernabé - Technical Staff 
  • Ramón González - Technical Staff 
  • Arnau Jaumandreu - Technical Staff 
  • Dr. Vega Lloveras - Technical Staff 
  • Albert Revuelta - Technical Staff 
  • Xavier Rodríguez - Technical Staff 

Left: Representation of the high-throughput method for studying cell motility on modified surfaces with nanoparticles. Right: Schematic representation of the organic electronic device using a new type of electrolyte‐gated organic field‐effect transistor showing memory.


  •   Positive pre-clinicain-vivo evaluation of peptide targeted nanoliposomes loaded with alfa-galactosidase (WO2014/001509) for intravenous treatment of Fabry disease. 
  • Quatsomes nanovesicles for intravenous drug-delivery and bioimaging have been developed. 
  • Fluorescent organic nanopoarticles (FONs) for bioimaging and theranostics, with unprecedented colloidal and photo stability. These FONs are based on quatsome nanovesicles containing a pair of fluorescent molecules that give rise to Förster resonance energy transfer (FRET). 
    • Enhancement of cell guidande on surfaces using a strategy based on the covalent anchoring of bacteria-based protein nanoparticles.  
    • Circularly polarized luminescence magnetic emitters with high racemization barrier using enantiopure propeller-like trityl-brominated organic radicals. 
  • Development of a 3D hydrogel which mimics the properties of the lymph node and improves the ex-vivo expansion of primary human CD4+ T cells.  
  • Application of two new patents: “A synthetic hydrogels and its use for Immunotherapy and 3D Printing” (EP20382432.1), and “An electrolyte-gated field-effect transistor” (P19382312.7) 
    • Fully water-soluble new polyphosphorhydrazone-based radical dendrimers have been developed by using an innovative synthetic procedure. A remarkable four times higher relaxivity compared with the gold-standard Gd-based CA, used in clinics, have been achieved either in vitro or ex vivo. 
    • Development of new organic polyradicals as redox mediators. We have demonstrated for the first time that the intramolecular spin-spin interactions play an important role on their electrochemical potential and their redox mediator behaviour. 
    • Preparation of a resistive switching device based on the use of a eutectic gallium-indium electrode with its native gallium oxide skin placed in contact with a graphene substrate.  
    • Low-cost organic field-effect transistors as X-ray detectors with unprecedented sensitivity. 
    • Organic field-effect transistors for biosensing alpha-synuclein (a Parkinson biomarker) with high sensitivity and for recording the activity of cardiomyocytes  cells. 

Stabilisation of surface-induced polymorphs of organic semiconductors by blending them with insulating polymers ensuring long-term device stability.  


Enhancing long-term device stability using thin film blends of small molecule semiconductors and insulating polymers to trap surface-induced polymorphs.  
T. Salzillo, A. Campos, A. Babuji, R. Santiago, S. T. Bromley, C. Ocal, E. Barrena, R. Jouclas, C. Ruzie, G. Schweicher, Y. H. Geerts, M. Mas-Torrent 
Adv. Funct. Mater. 2020,  30, 52, 2006115, 10.1002/adfm.202006115 

Nanoscale mapping of the conductivity and interfacial capacitance of an electrolyte-gated organic field-effect transistor under operation.  
A. Kyndiah, M. Checa, F. Leonardi, R. Millan-Solsona, M. Di Muzio, S. Tanwar, L. Fumagalli, M. Mas-Torrent, G. Gomila 
Adv. Funct. Mater. 2020, 31, 5, 2008032, 10.1002/adfm.202008032 

Selection of the room temperature enantiotropic polymorphs of diF-TES-ADT in solution sheared thin film transistors.  
T. Salzillo, N. Montes, R. Pfattner, M. Mas-Torrent 
J. Mater. Chem. C 2020, 8, 15361-15367, 10.1039/D0TC03222K   

Bioelectronic recordings of cardiomyocytes with accumulation mode electrolyte gated organic field effect transistors.  
A. Kyndiah, F. Leonardi, C. Tarantino, T. Cramer, R. Millan-Solsona, E. Garreta, N. Montserrat, M. Mas-Torrent, G. Gomila 
Biosensors and Bioelectronics 2020, 150, 111844, 10.1016/j.bios.2019.111844 

Crystal alignment of surface stabilized polymorph in thioindigo films  
A. Rivalta, A. Giunchi, L. Pandolfi, T. Salzillo, S. d’Agostino, O. Werzer, B. Schrode, N. Demitri, M. Mas-Torrent, A. Brillante, R.G. Della Valle, E. Venuti  
Dye. Pigment. 2020, 172, 107847, 10.1016/j.dyepig.2019.107847 

Use of N-oxide and cationic surfactants to enhance antioxidant properties of (+)-usnic acid loaded liposomes  
S. Battista, P. Campitelli, L. Galantini, M. Köber, G. Vargas-Nadal, N. Ventosa, L. Giansanti  
Colloids Surfaces A Physicochem. Eng. Asp. 2020, 585, 124154, 10.1016/j.colsurfa.2019.124154   

MKC-Quatsomes: a stable nanovesicle platform for bio-imaging and drug-delivery Applications  
G. Vargas-Nadal, M. Muñoz-Úbeda, P. Álamo, M. Mitjans, V. Céspedes, M. Köber, E. González-Mira, L. Ferrer-Tasies, M.P. Vinardell, R. Mangues, J. Veciana, N. Ventosa  
Nanomedicine Nanotechnology, Biol. Med. 2020, 24, 102136, 10.1016/j.nano.2019.102136   

Exploiting the versatile alkyne-based chemistry for expanding the applications of a stable triphenylmethyl organic radical on surfaces  
J.A. de Sousa, F. Bejarano, D. Gutiérrez, Y.R. Leroux, E.M. Nowik-Boltyk, T. Junghoefer, E. Giangrisostomi, R. Ovsyannikov, M.B. Casu, J. Veciana, M. Mas-Torrent, B. Fabre, C. Rovira, N. Crivillers   
Chem. Sci. 2020, 11, 516-524, 10.1039/C9SC04499J 

Fully Water-Soluble Polyphosphorhydrazone-Based Radical Dendrimers Functionalized with Tyr-PROXYL Radicals as Metal-Free MRI T1 Contrast Agents  
L.F. Pinto, V. Lloveras, S. Zhang, F. Liko, J. Veciana, J.L. Muñoz-Gómez, J. Vidal-Gancedo  
ACS Appl. Bio Mater. 2020, 3, 369–376, 10.1021/acsabm.9b00855 

An Enantiopure Propeller-Like Trityl-Brominated Radical: Bringing Together a High Racemization Barrier and an Efficient Circularly Polarized Luminescent Magnetic Emitter  
P. Mayorga-Burrezo, V.G. Jiménez, D. Blasi, T. Parella, I. Ratera, A.G. Campaña, J. Veciana  
Chem. – A Eur. J. 2020, 26, 3776–3781, 10.1002/chem.202000098 

Molecular Approach to Electrochemically Switchable Monolayer MoS2 Transistors  
Y. Zhao, S. Bertolazzi, M.S. Maglione, C. Rovira, M. Mas-Torrent, P. Samorì  
Adv. Mater. 2020, 32, 19, 2000740, 10.1002/adma.202000740 

Morphology and mobility as tools to control and unprecedentedly enhance X-ray sensitivity in organic thin-films  
I. Temiño, L. Basiricò, I. Fratelli, A. Tamayo, A. Ciavatti, M. Mas-Torrent, B. Fraboni  
Nat. Commun. 2020, 11, 2136, 10.1038/s41467-020-15974-7 

Dye-Loaded Quatsomes Exhibiting FRET as Nanoprobes for Bioimaging  
J. Morla-Folch, G. Vargas-Nadal, T. Zhao, C. Sissa, A. Ardizzone, S. Kurhuzenkau, M. Köber, M. Uddin, A. Painelli, J. Veciana, K.D. Belfield, N. Ventosa  
ACS Appl. Mater. Interfaces. 2020, 12, 20253–20262, 10.1021/acsami.0c03040 

Cyclodextrin-based superparamagnetic host vesicles as ultrasensitive nanobiocarriers for electrosensing  
J. Muñoz, N. Crivillers, B.J. Ravoo, M. Mas-Torrent  
Nanoscale 2020, 12, 9884–9889, 10.1039/D0NR01702G 

Neutral Organic Radical Formation by Chemisorption on Metal Surfaces  
M.R. Ajayakumar, C. Moreno, I. Alcón, F. Illas, C. Rovira, J. Veciana, S.T. Bromley, A. Mugarza, M. Mas-Torrent  
J. Phys. Chem. Lett. 2020, 11, 3897–3904, 10.1021/acs.jpclett.0c00269 

Electronic Performance of Polymer Carbon-Paste Nanoallotropes from 0D to 3D as Novel Gate Electrodes in Water-Gated Organic Field-Effect Transistors  
A. Tamayo, J. Muñoz, M. Mas-Torrent  
Adv. Electron. Mater. 2020, 6, 2000431, 10.1002/aelm.202000431 

Selective Discrimination of Toxic Polycyclic Aromatic Hydrocarbons in Water by Targeting π-Stacking Interactions  
J. Muñoz, Á. Campos-Lendinez, N. Crivillers, M. Mas-Torrent  
ACS Appl. Mater. Interfaces 2020, 12, 26688–26693, 10.1021/acsami.0c05557 

Stable anchoring of bacteria-based protein nanoparticles for surface enhanced cell guidance  
M. Martínez-Miguel, A.R. Kyvik, L. M. Ernst, A. Martínez-Moreno, O. Cano-Garrido, E. Garcia-Fruitós, E. Vazquez, N. Ventosa, J. Guasch, J. Veciana, A. Villaverde, I. Ratera 
J. Mater. Chem. B. 2020, 8, 5080–5088, 10.1039/D0TB00702A  

Synthesis of 0D to 3D hybrid-carbon nanomaterials carrying platinum(0) nanoparticles: Towards the electrocatalytic determination of methylparabens at ultra-trace levels  
J. Muñoz, I. Álvarez-Prada, E. Lopez-Lopez, L. Escriche, N. Romero, X. Sala, M. Mas-Torrent, J. García-Antón 
Sensors Actuators B Chem. 2020, 305, 127467, 10.1016/j.snb.2019.127467   

Highly Oxidized States of Phthalocyaninato Terbium(III) Multiple-Decker Complexes Showing Structural Deformations, Biradical Properties and Decreases in Magnetic Anisotropy  
Y. Horii, M. Damjanović, M.R. Ajayakumar, K. Katoh, Y. Kitagawa, L. Chibotaru, L. Ungur, M. Mas-Torrent, W. Wernsdorfer, B.K. Breedlove, M. Enders, J. Veciana, M. Yamashita  
Chem. – A Eur. J. 2020, 26, 8621–8630, 10.1002/chem.202001365   

Double Beneficial Role of Fluorinated Fullerene Dopants on Organic Thin-Film Transistors: Structural Stability and Improved Performance  
A. Babuji, I. Temiño, A. Pérez-Rodríguez, O. Solomeshch, N. Tessler, M. Vila, J. Li, M. Mas-Torrent, C. Ocal, E. Barrena  
ACS Appl. Mater. Interfaces 2020, 12, 28416–28425, 10.1021/acsami.0c06418   

Effects of Water and Different Solutes on Carbon-Nanotube Low-Voltage Field-Effect Transistors  
A.M. Foudeh, R. Pfattner, S. Lu, N.S. Kubzdela, T.Z. Gao, T. Lei, Z. Bao  
Small 2020, 16, 34, 2002875, 10.1002/smll.202002875   

Tris-pyridylmethylamine (TPMA) complexes functionalized with persistent nitronyl nitroxide organic radicals  
E. Badetti, V. Lloveras, F.A. Scaramuzzo, K. Wurst, J. Veciana, J. Vidal-Gancedo, G. Licini, C. Zonta  
Dalt. Trans. 2020, 49, 10011–10016, 10.1039/D0DT01553A 

Label-free immunodetection of α-synuclein by using a microfluidics coplanar electrolyte-gated organic field-effect transistor  
S. Ricci, S. Casalini, V. Parkula, M. Selvaraj, G.D. Saygin, P. Greco, F. Biscarini, M. Mas-Torrent  
Biosens. Bioelectron. 2020, 167, 112433, 10.1016/j.bios.2020.112433   

CCL21-loaded 3D hydrogels for T cell expansion and differentiation  
E. Pérez Del Río, F. Santos, X. Rodriguez Rodriguez, M. Martínez-Miguel, R. Roca-Pinilla, A. Arís, E. Garcia-Fruitós, J. Veciana, J.P. Spatz, I. Ratera, J. Guasch  
Biomaterials 2020, 259, 120313, 10.1016/j.biomaterials.2020.120313   

Radical dendrimers based on biocompatible oligoethylene glycol dendrimers as contrast agents for MRI  
S. Zhang, V. Lloveras, D. Pulido, F. Liko, L.F. Pinto, F. Albericio, M. Royo, J. Vidal-Gancedo  
Pharm 2020, 12, 772, 10.3390/pharmaceutics12080772 

Stability of radical-functionalized gold surfaces by self-assembly and on-surface chemistry  
T. Junghoefer, E.M. Nowik-Boltyk, J.A. de Sousa, E. Giangrisostomi, R. Ovsyannikov, T. Chassé, J. Veciana, M. Mas-Torrent, C. Rovira, N. Crivillers, M.B. Casu  
Chem. Sci. 2020, 11, 9162–9172, 10.1039/D0SC03399E 

Organic Polyradicals as Redox Mediators: Effect of Intramolecular Radical Interactions on Their Efficiency  
E. Badetti, V. Lloveras, E. Amadio, R. Di Lorenzo, M. Olivares-Marín, A.Y. Tesio, S. Zhang, F. Pan, K. Rissanen, J. Veciana, D. Tonti, J. Vidal-Gancedo, C. Zonta, G. Licini 
ACS Appl. Mater. Interfaces 2020, 12, 45968–45975, 10.1021/acsami.0c09386 

Dibenzocycloheptatriene as end-group of Thiele and tetrabenzo-Chichibabin hydrocarbons  
V.G. Jiménez, P. Mayorga-Burrezo, V. Blanco, V. Lloveras, C.J. Gómez-García, T. Šolomek, J.M. Cuerva, J. Veciana, A.G. Campaña  
Chem. Commun. 2020, 56, 12813–12816, 10.1039/D0CC04489J 

Electrocatalytic oxidative: Z/E isomerization of a stilbene favoured by the presence of an electroactive persistent radical  
P. Mayorga-Burrezo, C. Sporer, J.A. de Sousa, N. Capra, K. Wurst, N. Crivillers, J. Veciana, C. Rovira 
Chem. Commun. 2020, 56, 14211–14214, 10.1039/D0CC04973E 

Resistive switching observation in a gallium-based liquid metal/ graphene junction  
D. Gutiérrez, J.A. de Sousa, M. Mas-Torrent, N. Crivillers  
ACS Appl. Electron. Mater. 2020, 2, 3093–3099, 10.1021/acsaelm.0c00296   

Reversal of the Direction of Rectification Induced by Fermi Level Pinning at Molecule-Electrode Interfaces in Redox-Active Tunneling Junctions  
Y. Han, M.S. Maglione, V. Diez Cabanes, J. Casado-Montenegro, X. Yu, S.K. Karuppannan, Z. Zhang, N. Crivillers, M. Mas-Torrent, C. Rovira, J. Cornil, J. Veciana, C.A. Nijhuis  
ACS Appl. Mater. Interfaces 2020, 12, 55044–55055, 10.1021/acsami.0c15435 

Outreach activities

  • Diffusion of Nanomol products and technologies offers at the Open Innovation Forum organized by Biocat. 
  • Coordination of the Nanotechnology for Therapy and Remediation Module of the Master in Advanced Nanoscience and Nanotechnology (UAB) by Imma Ratera  
  • Press appearances about our work on organic transistors for cell activity monitoring in La Vanguardia. 
  • Participation within a CSIC initiative in the recording of video to promote women in science. 
  • Invited talk on “Particulate materials for drug delivery” for ClarivateCortellis Drug Discovery Intelligence, given by Nora Ventosa 
  • Participation of Nora Ventosa in the Unprecedented Webinar:Tech Transfer: Ciencia e Industria en Acción, organized by Expoquimia 
  • Press appearance of Nora Ventosa at the radio program la “Nit dels Ignorants” of Catalunya Radioto talk about COVID-19 from a chemists' point of view. 
  • Training course about different techniques for characterizing particulate materials. 
  • Judith Guasch is interviewed by the newspapers “Diari de Tarragona” and “El 3 de vuit”, as well as the digitals “Innovaspain” and “Agencia SINC” to speak about hydrogels for cancer immunotherapy. 
  • Judith Guasch is interviewed by CosmoCaixa (Science Museum of Barcelona) about Biomimetic Materials. 
  • Judith Guasch speaks about hydrogels for cancer immunotherapy on “Radio Nacional de Epaña” in the program “A hombros de gigantes” as well as in “De Cero al Infinito” de “Onda Cero Radio”. 
  • News about “3D hydrogels for Cancer Immunotherapy” in more than 25 digital publications, including “La Vanguardia”“National Geographic España”“COPE”“El Independiente”and “MSN”.   


Renewed TECNIO certification which accredits the Research Group as a Technology Developer Organization for the period 2020-2023. The TECNIO certification is created by the Government of Catalunya, through ACCIÓ. TheTECNIO certification supports the most qualified agents involved in technology transfer processes, allows companies to access advanced R&D and develop new products and services, and increases the scope of technology projects by finding the most suitable technology partners and suppliers. 

Dr. Manuel Souto awarded with the European Award for Doctoral Thesis of the European Institute of Molecular Magnetism. 

Main projects

Member of Centro de Investigación Biomédica en Red – Bioengineering, Biomaterials and Nanomedicine  
Jaume Veciana 

Smart-4-Fabry (ref.720942): Smart multifunctional GLA-Nanoformulation for treating Fabry Disease 
H2020 EU project 
Nora Ventosa 

NANO-OLIGOMED (ref. 778133): Hybrid nanostructured oligonucleotide platforms for biomedical applications” 
EU project. H2020-MSCA-RISE-2017 
Luisa de Cola, Nora Ventosa 

Fluorescent organic nanoparticles for bioimaging (FONBIO) (ref. TECSPR17-1-0035) 
Judit Morlà 

TAGSMARTLY “Targeted Quatsome nanocarriers for the delivery of microRNA for neuroblastoma therapy”  
Nora Ventosa, Mariana Köber 

Rising the Impact of Selected Engineered Bacterial Cellulose composites (RICE-BC) 
RTI2018-096273−B-I00 Ministerio de Ciencia, Innovación y Universidades  

Materiales moleculares y organizaciones supramoleculares para terapia, diagnosis e ingeniería tisular (MOTHER) 
MAT2016-80826-R MINECO Retos 
Jaume Veciana, Nora Ventosa  

FANCY: "Functional organic materials for the Fabrication of sensors and (spin)-electronic/memory devices”  
Spanish Ministry, CTQ2013-40480-R 
Marta Mas-Torrent, Concepció Rovira 

Procesamiento de moléculas para crear materiales híbridos estructurados jerárquicamente para aplicaciones biomédicas (Mol4Bio)  
PID2019-105622RB-I00 MINECO Retos 
Nora Ventosa, Imma Ratera  

GENESIS: “Engineering, preparation and characterisation of organic-based high performing Electronic devices for physical and bio-sensing applications and for the development of new emerging technologies” 
Spanish Ministry 
Marta Mas-Torrent, Núria Crivillers  

Between Atom and Cell: Integrating Molecular Biophysics Approaches for Biology and Healthcare (MOBIEU) 
CA15126  ESF - COST Action 
Imma Ratera  

Lymph node-inspired 3D printed hydrogels for adoptive cell therapy (Gels4ACT) 
Judith Guasch, Jaume Veciana  

Dynamic Biomimetics for Cancer Immunotherapy 
Max Planck Partner Group; Max Planck Society 
Judith Guasch  

Ramón y Cajal program (RYC-2017-22614) 
Spanish Ministry 
Judith Guasch  

Prevention of vascular catheter-related infections by the FUNctionalization of CATHeters with thermically activated hydrogels with antimicrobial agents of broad spectrum (FUNCATH) 
Fundació La Marató de TV3  
Imma Ratera  

Red de Dendrímeros para aplicaciones Biomédicas 
Rafael Gómez Ramirez, José Vidal Gancedo  

Radicales y dendrímeros radicales para imagen de Resonancia Magnética Nuclear y otras aplicaciones bio 
201760E080 Intramural CSIC 
José Vidal Gancedo  

UHMob:"Ultra-high Charge Carrier Mobility to Elucidate Transport Mechanisms in Semiconductors" 
Yves Geerts, Marta Mas-Torrent 

Organic Radicals as Molecular Quantum Bits (RadicalQBits) 
ILINK-A-2018, Internationalization project from CSIC 
Nuria Crivillers 

BIO-PAD: "Biosensor platform based on organic transistors for the diagnosis of Alzheimer desease” 
Spanish Ministry MAT2015-72760-EXP 
Marta Mas-Torrent 

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Web & Graphic Editor
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